Yevgeny Brudno

Yevgeny Brudno, PhD, is an Associate Professor at the Eshelman School of Pharmacy (UNC-Chapel Hill) with a joint appointment in Biomedical Engineering (UNC and NC State University). He is a member of the UNC Lineberger Comprehensive Cancer Center and leads the Brudno Lab, which specializes in drug delivery and biomaterials for cancer immunotherapy, particularly CAR T cell therapy.

• Research Focus: Development of implantable biotechnologies for in vivo CAR-T cell production, biomaterials for therapeutic delivery, and click chemistry-based drug targeting.
• Education: PhD (unspecified institution).

The lab’s research bridges chemical and biomaterials science with clinical needs, emphasizing on-demand drug release, solid tumor targeting, and autoimmune disease treatments. Recent work includes bioinstructive scaffolds and tissue-reactive drug depots, leveraging click chemistry and nanomedicine.

His scientific contributions are highlighted by 15 publications (2009–2025) in fields like biotechnology, cancer immunotherapy, and epigenetics. Notable awards include the NCI MERIT Award, University Faculty Scholar (NC State), and Outstanding Teacher Award (NC State).

Advising: Mentored 13 PhD and Master’s students, including Sharda Pandit (2023), Chris Moody (2021), and Emily Joe (2024). Lab announcements highlight student achievements like NSF and NIH fellowships.

The Brudno Lab collaborates with UNC Lineberger and NC State, focusing on streamlining therapy production, enhancing efficacy in solid tumors, and autoimmune disease applications, supported by grants from NCI and CMI.