Yang Xie

Yang Xie is a Professor at UT Southwestern Medical Center, where she serves as the Associate Dean for Data Sciences. She is the founding director of the Quantitative Biomedical Research Center (QBRC), Pediatric Cancer Data Commons (PCDC), and Cancer Center Data Science Shared Resources (DSSR) within the Harold C. Simmons Comprehensive Cancer Center. Her research integrates biostatistics, bioinformatics, and machine learning to develop predictive biomarkers and precision medicine approaches for cancer patients.

Her PhD in Biostatistics (2006) and MS in Biostatistics (2002) and Epidemiology (2000) from University of Minnesota-Twin Cities and Peking University Health Science Center (1997) form the foundation of her interdisciplinary expertise. Research focuses include RNA regulation, high-dimensional data analysis, and computational oncology.

Recent projects leverage deep learning for pathology image analysis and tumor microenvironment modeling, with applications in lung cancer survival prediction, Germ Cell Tumor data commons, and immune-related adverse event forecasting. She has developed open-source tools like MetaPrism and PIPE-CLIP for microbiome and CLIP-seq analysis.

Scientific recognitions include NIH MIRA grant leadership and multiple DREAM Challenge awards for computational modeling. Her work bridges biostatistics, machine learning, and translational oncology through collaborations with institutions like MD Anderson and Northwestern University.