Xupei Huang

Xupei Huang, M.D., Ph.D., is a Professor in Biomedical Science at the Charles E. Schmidt College of Medicine, Florida Atlantic University (FAU). He has been affiliated with FAU since 2001 and previously held a Research Assistant Professor position at Texas A&M University (1996-2001). Huang earned his M.D. from Nanjing Medical University (1985) and Ph.D. in Biochemistry from University of Paris XII (1992).

• Research Focus: Mechanisms and treatment of cardiomyopathies and heart failure, with expertise in intracellular signaling, gene regulation, and transgenic animal models.
• Key Contributions: 80+ peer-reviewed papers on cardiac troponin mutations, epigenetic modifications, and pharmacological interventions like green tea catechins.
• Teaching: Leads the Cardiovascular System curriculum for medical students.
• Editorial Role: Associate Editor for the journal Cardiology.

Article Trends: Recent work spans epigenetic mechanisms (histone acetylation, methylation) in cardiomyopathy, translational therapies (EGCG, sulindac derivatives), and genetic mouse models of restrictive cardiomyopathy. His lab explores oxidative stress pathways, contractile protein dynamics, and nuclear roles of cardiac proteins like troponin I.

Labs & Collaborations: Huang’s research group at FAU collaborates on pediatric heart disease translational studies and investigates cardiac gene therapies using AAV vectors.