معرفی
Dr Xin Gao is a researcher at the Division of Immunology and Infectious Diseases, The Australian National University. His work focuses on understanding immune responses, particularly B cell dynamics, germinal center biology, and T follicular helper (Tfh) cell functions. Key research areas include CD11c+ atypical B cells, IL-21 signaling in germinal centers, and Tfh17-driven immunological memory. His studies explore mechanisms underlying vaccine efficacy, pathogen persistence, and autoimmune processes.
Research interests span molecular immunology, cytokine regulation, and cellular differentiation pathways. He investigates how B cell subsets contribute to immune memory and vaccine protection, with a focus on transcription factors like ZEB2 and signaling molecules such as heparan sulfate-modulated IL-21. Collaborations include studies on malaria immunity and the role of metabolic hormones like leptin in Tfh cell function.
His publications highlight contributions to understanding plasma cell formation, germinal center waning processes, and the interplay between innate and adaptive immune components. Ongoing work addresses improving vaccine strategies through insights into immune longevity and antigen-specific responses.
