معرفی
Xiaohong Wu is a Researcher in the Department of Internal Medicine at Yale School of Medicine. Her work focuses on metabolic signaling pathways and their roles in cardiac function, particularly in conditions like heart failure and atrial fibrillation. She collaborates frequently with investigators such as Fadi Akar, Lawrence Young, and Gerald Shulman.
Her research explores mechanisms linking AMPK pathway dysfunction to cardiac arrhythmias and metabolic remodeling, with recent studies on SGLT2 inhibitors' effects on heart failure and mitochondrial function. Publications highlight contributions to understanding post-ischemic recovery, pulmonary vein arrhythmogenesis, and diet-induced cardiac electrophysiological changes.
Key collaborators include Fadi Akar (AMPK studies), Dongyan Zhang (heart failure models), and Jiasheng Zhang (cardiac imaging). Her studies utilize mouse and rat models to dissect metabolic-cardiac interactions, with findings published in journals like Journal of Clinical Investigation and Heart Rhythm.