معرفی
Dr. Xiao Wang is a Research Fellow at Newcastle University's Institute of Cellular Medicine in the School of Medical Sciences. Their work focuses on immunology, stem cell research, and regenerative medicine, particularly in the context of graft-versus-host disease (GVHD) and osteoarthritis.
Research interests include:
- MSC-derived extracellular vesicles for tissue repair
- MicroRNA profiling in inflammatory diseases
- Regulatory T cell mechanisms in GVHD suppression
- 3D bioprinting for osteochondral models
- Immunomodulatory properties of fibroblasts and MSCs
- Pathogenesis of autoimmune and transplant-related complications
Scientific contributions emphasize the role of dendritic cells, mesenchymal stromal cells, and their interactions in alloimmune responses. Key trends include:
- Development of in vitro human skin explant models for GVHD
- Investigation of miRNA signatures as biomarkers
- Optimization of cell therapies through EVs and bioprinting
- Elucidation of chemokine signaling in immune cell trafficking
- Analysis of HSP70 gene polymorphisms in transplant outcomes
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