معرفی
Xiao Wang is the Thomas D. and Virginia Cabot Associate Professor of Chemistry at the Massachusetts Institute of Technology (MIT) and a Core Member of the Broad Institute of MIT and Harvard. His research focuses on developing chemical and biophysical tools to study molecular events in the brain, including spatial transcriptomics, in-situ sequencing, and imaging methods. The Wang Group works at the intersection of chemistry, biophysics, and genomics to map brain wiring and function at unprecedented resolution.
Key research areas include spatial omics technologies for single-cell resolution, RNA modification engineering, and applications in neuroscience and therapeutics. The lab is known for pioneering methods like STARmap and ClusterMap for spatial gene expression analysis. Recent work extends to AI-driven spatial transcriptomics and optimizing mRNA translation capacity through chemical design.
Publications highlight innovations in spatial multi-omics, mRNA therapeutics, and neurobiological mechanisms. The lab collaborates extensively with institutions like Harvard Medical School and the Broad Institute. Current projects emphasize scalable spatial tools and translational applications of molecular imaging.
Advising and grants: Xiao Wang mentors over 20 PhD students and postdocs. Funding includes support from the Damon Runyon Foundation (Wendy Wang) and NIH grants. The lab actively recruits postdocs and students through MIT’s Chemistry and related departments.
Labs/teams: The Wang Group operates at MIT and the Broad Institute, leveraging interdisciplinary approaches to address challenges in molecular neuroscience and precision medicine.
