
معرفی
Xavier De Bolle is a Researcher at the University of Namur, affiliated with the Research Unit in Biology of Microorganisms under the Namur Research Institute for Life Sciences. His work focuses on Brucella abortus pathogenesis, integrating cell cycle regulation, outer membrane biogenesis, and host-pathogen interactions.
Research highlights:
- Decades-long exploration of Brucella developmental processes linked to virulence
- Pioneering studies on CtrA regulatory protein and PdhS histidine kinase in bacterial polarity
- Investigations into G1 phase cell cycle arrest as an infectious mechanism
- Leveraging microscopy and genetic screening to understand pathogen morphology
Key collaborations:
- Co-investigator in ARC 17/22-087 (outer membrane biogenesis)
- Principal Investigator for BRUCELL-CYCLE and MICRO-BL3 projects
- Contributor to MICRODEV program on pathogen developmental virulence
Supervision: Mentored multiple Doctor of Science candidates, including Hallez R., Laloux G., and Deghelt M., guiding research on bacterial signaling, membrane dynamics, and infection mechanisms.
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