Woojin An

Dr. Woojin An is a Professor of Cancer Biology at the Keck School of Medicine of the University of Southern California (USC). He joined USC's faculty in 2004 following postdoctoral training at the Rockefeller University and earned his Ph.D. in Biochemistry and Biophysics from Oregon State University in 1998. His research focuses on epigenetic histone remodeling, exploring how histone modifications, variant exchanges, and proteolysis regulate chromatin structure and gene expression in cancer, differentiation, and cellular transformation.

Key research areas include histone H2A phosphorylation, MMP-mediated histone tail proteolysis, and epigenetic mechanisms in osteoclastogenesis and tumor progression. His work spans disciplines such as molecular biology, cancer biology, and genomics, with a focus on understanding how chromatin dynamics contribute to oncogenesis and therapeutic resistance.

Dr. An’s publications highlight his exploration of histone-modifying enzymes (e.g., VprBP/DCAF1, MLL1), their roles in gene silencing and transcriptional regulation, and their implications in diseases like melanoma, colon cancer, and chronic kidney disease. His lab employs cutting-edge techniques like epigenome-wide association studies and proteomic analysis to dissect these mechanisms.

No scientific awards are explicitly listed in the provided profile. Advising and grants are not detailed here, but his research has likely been supported by grants given his prolific publication record. His laboratory at USC is a hub for studying chromatin biology and its clinical applications.