William Nyberg

William A. Nyberg is an Assistant Professor at the Department of Medicine, Huddinge, Karolinska Institutet. His research focuses on the in vivo genetic modification of T cells for cancer treatment, utilizing chimeric antigen receptors (CARs), CRISPR/Cas9, and synthetic vectors like adeno-associated viruses (AAVs) and lipid nanoparticles (LNPs). The lab aims to eliminate time-consuming ex vivo manufacturing processes and enhance CAR-T cell efficacy in immunosuppressive tumor microenvironments.

• Assistant Professor, Department of Medicine, Huddinge (2024–2030)
• SciLifeLab Fellow (2024–2030)
• European Research Council grant recipient (2025–2029)
• Recruiting postdoctoral fellows, doctoral, and master's students

His work intersects Genetic Engineering, Immunology, and Oncology, with key subfields including CAR-T cell therapy, CRISPR/Cas9, tumor microenvironment, and synthetic biology. Collaborative projects involve Yenan Bryceson's group and translational humanized/syngeneic mouse models.

Scientific Awards:

• SciLifeLab Fellow (Karolinska Institute, 2024–2030)

Advising:

• Julian Fischbach (Doctoral student)