Wei-Ling Tsou

Dr. Wei-Ling Tsou is a Researcher in the Department of Pharmacology at Wayne State University School of Medicine, specializing in age-related neurodegeneration and proteinopathies. Her work focuses on Spinocerebellar Ataxias (SCAs) and Parkinson’s Disease (PD), using Drosophila melanogaster and cell culture systems to study protein aggregation, oxidative stress, and therapeutic interventions.

• Ph.D. in Neuroscience, National Yang-Ming University, Taipei, Taiwan
• Post-doctoral fellow and Research Associate in Pharmacology, Wayne State University

Research interests include:

• Protein aggregation mechanisms in PD and SCAs
• Polyamine metabolism in neurotoxicity and neuroprotection
• Ubiquitin-proteasome system and protein quality control
• Development of Drosophila models for neurodegenerative diseases

Her publications span molecular neuroscience, genetics, and environmental toxicology, with recent work exploring:

• Therapeutic targeting of polyamine pathways in PD (2025)
• Mechanistic roles of ataxin-3 domains in SCA3 toxicity (2024-2023)
• Protein interactions in polyglutamine diseases (2022-2011)

Dr. Tsou mentors graduate students and research assistants, emphasizing experimental design and troubleshooting. She has presented her findings at national and international conferences and contributes to scientific discourse through her research on neurodegenerative disease mechanisms.