Wanding Zhou

Wanding Zhou is an Assistant Professor at the Perelman School of Medicine, University of Pennsylvania, and affiliated with Children's Hospital of Philadelphia in the Department of Pathology and Laboratory Medicine. His research focuses on computational epigenetics, leveraging DNA methylation as a robust readout of chromatin state and cell identity.

• Ph.D. in Bioengineering from Rice University (2013)

His work spans epigenetics and chromatin, bioinformatics and genomics, with applications in cancer genetics, developmental genetics, and human genetics. Zhou develops computational methods for DNA methylation assays, including Infinium microarrays and bisulfite-sequencing, targeting single-cell and low-input experiments.

Recent publications highlight advances in DNA methylation harmonization, single-cell analytics, and multi-omics integration for studying cellular aging, tumor heterogeneity, and developmental abnormalities. His lab emphasizes data science and statistical machine learning in biomedical research.