Guoping Fan

Guoping Fan is a Professor in the Department of Human Genetics at the David Geffen School of Medicine, University of California, Los Angeles (UCLA). His research focuses on the interplay between DNA methylation, chromatin remodeling, and neural development, with significant contributions to understanding epigenetic mechanisms in stem cell differentiation, reprogramming, and disease modeling. Key areas of interest include

• Epigenetic regulation of gene expression
• Neuronal function and development
• Stem cell biology (pluripotent and mesenchymal stem cells)
• Retinal pigment epithelium differentiation
• Single-cell multi-omics profiling

Recent publications highlight his work on DNA/RNA methylation crosstalk (2025), hydrogel-mediated cell differentiation (2024), and single-cell epigenetic analysis of retinal organoids (2023). His studies span neurogenetics, cancer epigenetics, and bioengineering applications.

His laboratory at UCLA explores molecular mechanisms linking epigenetics to developmental disorders and regenerative medicine, utilizing advanced techniques like single-cell RNA sequencing and chromatin accessibility profiling. No explicit awards or advisees are mentioned in the provided text.