معرفی
Dr. Wael M. Rabeh is an Associate Professor of Chemistry at New York University Abu Dhabi (NYUAD), affiliated with the Division of Science. He holds a PhD in Biochemistry from the University of Oklahoma and conducted postdoctoral research at the Structural Genomic Consortium (University of Toronto) and McGill University. His research focuses on protein structure-function relationships, particularly in disease-relevant proteins such as CFTR (cystic fibrosis transmembrane conductance regulator) and human Hexokinase 2, leveraging X-ray crystallography and biophysical techniques. Key areas include cystic fibrosis mechanisms, cancer metabolism, drug discovery, and bioluminescence.
Dr. Rabeh’s work has contributed to understanding CFTR misfolding and functional correction, as well as the role of Hexokinase 2 in tumor growth. His lab collaborates internationally (e.g., with McGill University) and has secured funding from institutions like Al Jalila Foundation, Terry Fox Research Foundation, and NYUAD. He teaches courses in biochemistry and structural biology, emphasizing hands-on experimental approaches.
Notable research highlights include the discovery of a dual-step correction mechanism for the ∆F508 CFTR mutation and structural studies of antiviral drugs like Tamiflu. His lab’s bioluminescence research aims to elucidate color-producing mechanisms in luciferases. Dr. Rabeh actively contributes to structural biology education through innovative laboratory curricula and public engagement.
