Vyne van der Schoot

Vyne van der Schoot is a Researcher at Erasmus MC in the Department of Clinical Genetics, Rotterdam, Netherlands. Their work focuses on advancing prenatal genetic diagnostics and addressing ethical and regulatory challenges in modern genetic testing.

The research interests of Dr. van der Schoot span clinical genetics, prenatal diagnosis, exome and next-generation sequencing, genetic screening, and bioethical issues in reproductive genetics. Their work integrates molecular diagnostics with patient-centered care and policy analysis.

The recent publications highlight a strong trend in improving diagnostic accuracy in prenatal settings using advanced genomic technologies like exome sequencing and gene panels, while also critically examining the ethical and regulatory implications of emerging tools such as polygenic risk scoring in preimplantation testing. The interdisciplinary nature of the research combines laboratory science with qualitative and normative analysis.

Scientific Contributions:

• High diagnostic yield of prenatal exome sequencing in pregnancies with ultrasound anomalies.
• Evaluation of karyotyping utility post-NGS in prenatal confirmation.
• Ethical exploration of unsolicited findings in genetic testing.
• Regulatory analysis of preimplantation genetic testing across Europe.

Dr. van der Schoot actively collaborates with a multidisciplinary team at Erasmus MC, contributing to both clinical applications and policy discourse in medical genetics. While no formal advising or grant information is provided, their co-authorship on multiple peer-reviewed studies indicates active participation in funded research projects and national or international collaborations in clinical genomics.