Volker H. Haase

Volker H. Haase, MD, is a Professor in the Department of Medicine at Vanderbilt University School of Medicine, with additional appointments in Cancer Biology and Molecular Physiology and Biophysics. He holds the Krick-Brooks Chair in Nephrology and Hypertension. His research focuses on hypoxia response pathways, particularly their roles in erythropoiesis, iron metabolism, kidney injury, and tumorigenesis. The Haase Lab employs advanced techniques like mouse genetics and metabolomics to study mitochondrial metabolism in kidney diseases. Key areas include HIF-PHI therapies for anemia of chronic kidney disease (CKD) and the interplay between hypoxia signaling and cellular differentiation.

Haase's work has led to notable achievements, including the 2024 AAAS Fellowship for contributions to experimental and translational medicine. His lab collaborates widely, with recent studies on mitochondrial dysfunction in renal epithelium and erythropoietin-producing cells. Notable lab members include Dr. Ryoichi Bessho, who studies mitochondrial electron transport in kidney physiology.

• Education: MD (not explicitly stated in text, but title indicates medical training).

Research interests emphasize hypoxia-induced cellular adaptations, with a focus on kidney-specific mechanisms. The lab's findings have informed clinical applications like HIF-PHI drugs for CKD anemia. Recent studies also explore AMPK-dependent aquaporin regulation and FOXD1 lineage roles in anemia pathogenesis.

Scientific awards include the AAAS Fellowship, and his lab's innovations are highlighted in high-impact journals. Collaborations with the Arroyo Lab and others underscore interdisciplinary approaches to kidney and metabolic diseases.