Vlad Sandulache

Vlad C. Sandulache, MD, PhD is an Associate Professor and Vice Chair of Research at Baylor College of Medicine's Department of Otolaryngology-Head and Neck Surgery, where he serves as Chief of Service at MED VAMC. He is also affiliated with the Center for Translational Research on Inflammatory Diseases (CTRID) and the Dan L Duncan Comprehensive Cancer Center.

Research Focus: Dr. Sandulache's work centers on the intersection of cancer metabolism and treatment effectiveness, particularly in head and neck squamous cell carcinoma. His research explores how metabolic reprogramming influences responses to chemotherapy, radiation, and immunotherapy.

Scientific Contributions: Recent publications highlight his work on cisplatin resistance mechanisms, oxidative stress neutralization, TP53 mutation implications, immunometabolic determinants of treatment response, and ancestry-related cancer biology. These studies appear in journals like Clinical Cancer Research and Cancer Research.

Scientific Recognition:

• Fellow, American College of Surgeons

Grants & Funding: Active grants include

• National Cancer Institute: Hyperpolarized MRI for Precision Oncology
• National Cancer Institute: Targeting fatty acid metabolism for cisplatin resistance
• American Cancer Society: Tobacco exposure effects on oropharyngeal cancer immunity