Vijay Shah

Vijay Shah, M.D. is a Professor of Medicine and Physiology at Mayo Clinic, Rochester, MN, with primary appointments in the Division of Gastroenterology and Hepatology and the Department of Physiology & Biomedical Engineering. He currently serves as the Mr. and Mrs. Ronald F. Kinney Executive Dean of Research at Mayo Foundation for Medical Education and Research (2024–present), a leadership role reflecting his extensive contributions to academic medicine and research infrastructure.

• Carol M. Gatton Professor of Digestive Diseases Research, Mayo Clinic (2019)
• Distinguished Investigator Award, Mayo Clinic (2019)
• Inductee, Association of American Physicians (2020)
• Associate Editor, Journal of Hepatology (2014–present)
• Former Chair, Department of Medicine (2020–2024)
• Former Chair, Division of Gastroenterology and Hepatology (2013–2020)

Dr. Shah’s research focuses on chronic liver diseases, particularly alcohol- and nonalcohol-related cirrhosis, portal hypertension, and liver fibrosis. His work spans from laboratory-based mechanistic studies to translational and clinical trials, leveraging Big Data analytics and AI to improve diagnosis, prognosis, and treatment of liver disease. He leads multiple NIH-funded projects, including studies on alcoholic hepatitis, liver fibrosis, and advanced imaging techniques like magnetic resonance elastography.

The most recent publications highlight a strong trend toward interdisciplinary research, combining hepatology with artificial intelligence, immunology, and data science. Topics include AI-driven synthetic data generation, predictive ECG scoring in cirrhosis, and macrophage dynamics in liver congestion. These works reflect a shift toward integrative, technology-enhanced approaches in understanding and managing advanced liver disease.

• Research Award, Minnesota Partnership for Biotechnology and Medical Genomics (2022)
• Member, American Society of Clinical Investigation (ASCI)
• Board Liaison and Treasurer, American Association for the Study of Liver Diseases (AASLD)
• Standing Member, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), NIH

Dr. Shah has mentored numerous trainees and led major training programs, including the Multidisciplinary Training Grant in Digestive Diseases. He has served in leadership roles across Mayo Clinic and national organizations, overseeing research strategy, postdoctoral affairs, and clinical research infrastructure. He is actively involved in NIH grant review and advisory councils, shaping national research priorities in liver disease.

He leads key research centers such as the Mayo Center for Cell Signaling in Gastroenterology and the Liver Cirrhosis Network: Clinical Research Center. His lab and collaborative teams focus on molecular mechanisms of fibrosis, portal hypertension, and AI applications in hepatology. Current projects integrate genomics, proteomics, and advanced imaging to develop novel diagnostics and therapies for liver disease.