Vijay P. Singh

Roles and Affiliations:
Vijay P. Singh is a Professor of Medicine and Consultant in the Division of Gastroenterology and Hepatology at Mayo Clinic. He holds a joint appointment in the Department of Biochemistry and Molecular Biology. His primary affiliation is with Mayo Clinic in Phoenix/Scottsdale, Arizona.

Education:
• MBBS from Panjab University
• BS in Medical Lab Technology from Postgraduate Institute of Medical Education & Research
• Postdoctoral Fellowship at Harvard Medical School
• Advanced training in Gastroenterology at Mayo Clinic programs

Research Focus:
Dr. Singh’s work centers on the pathophysiology of acute/chronic pancreatitis, particularly mechanisms regulating acinar cell function (vesicular trafficking, cytoskeletal dynamics) and lipotoxicity. His lab investigates obesity’s role in exacerbating pancreatic injury, developing novel therapies like transgastric pancreatic hypothermia. Key areas include:

• Acinar cell injury and tyrosine phosphorylation
• Intracellular calcium homeostasis disruptions
• Pancreatitis-related multisystem organ failure
• Therapeutic translation from human evidence

Grants & Collaborations:
- NIH-funded studies on alcoholic pancreatitis biomarkers
- Army grants investigating acute lung injury comorbidity
- Military Medical Research Programs supporting pancreatic cooling therapies
- NIDDK grants exploring sepsis transitions in sterile pancreatitis

Awards & Recognition:
Awarded NIH study section roles, Digestive Disease Week honors, and international speaking engagements. His work has led to issued patents for pancreatitis treatments.

Labs & Projects:
Leads the Pancreatitis and Acute Outcomes Research Lab, focusing on real-time imaging, lipid behavior, and acute disease modeling. Collaborates globally on lipotoxicity and therapeutic innovation.