Vigdis Aas

Vigdis Aas is a Professor at Oslo Metropolitan University, Faculty of Health Sciences, Department of Life Sciences and Health. Her research is centered on human skeletal muscle physiology, metabolism, and intercellular signaling, with a strong emphasis on diabetes, obesity, and exercise-related adaptations.

Her research interests include Pharmacy, Physiology, Pharmacology, Metabolism, Diabetes, Signal Transduction, Exercise, and Extracellular Vesicles. She investigates how skeletal muscle cells respond to metabolic challenges, electrical stimulation (as an exercise model), and inflammatory triggers, with a focus on energy metabolism, insulin signaling, and secretory factors like myokines and extracellular vesicles.

The recent articles show a consistent trend in studying in vitro models of human skeletal muscle (myotubes), especially from obese and diabetic donors. Key themes include metabolic flexibility, the role of gut-derived metabolites (e.g., short-chain fatty acids), mitochondrial function, and inter-tissue communication via extracellular vesicles. Her work bridges molecular cell biology with clinical metabolic disease.

Scientific Contributions:

• Extensive publication record in journals such as Frontiers in Physiology, Scientific Reports, Journal of Lipid Research, and Acta Physiologica.
• Active dissemination at international conferences including ISEV, EASD, and NSFT.
• Development and application of in vitro exercise models using electrical pulse stimulation.

Research and Mentoring: Vigdis Aas leads and contributes to multiple research projects on extracellular vesicles, energy metabolism, and metabolic disease. She collaborates widely within OsloMet and beyond, mentoring junior researchers and students, though specific advisee names are not listed. Her work is supported by research funding and involves interdisciplinary teams focused on disease and environmental exposures.

Laboratory and Research Groups: She is part of the Disease and Environmental Exposures research group, utilizing cell culture models and omics technologies to explore metabolic adaptations in human skeletal muscle.