Vera Wiersma

Vera Wiersma is an Assistant Professor in the Department of Pathology at Vrije Universiteit Amsterdam, affiliated with Amsterdam Neuroscience. Her research focuses on neurodegenerative proteinopathies, particularly granulovacuolar degeneration (GVD) bodies in Alzheimer's disease and related disorders.

• Institution: Vrije Universiteit Amsterdam
• Department: Pathology
• Research Themes: Neurodegeneration, Tauopathy, Synucleinopathy

Her work investigates the cellular and molecular mechanisms of GVD bodies, their relationship to pathological protein aggregates like tau and α-synuclein, and their role in neuronal stress and disease progression. She employs in vitro and in vivo models to study these processes.

Recent publications highlight her contributions to understanding GVD pathogenesis, including its independence from CSPα/DNAJC5 deficiency and its association with Alzheimer's and Parkinson's disease mechanisms. Her research integrates cellular neuroscience and protein biochemistry to address neurodegenerative disease challenges.