Tufia C. Haddad

Dr. Tufia C. Haddad is a Professor of Oncology at Mayo Clinic College of Medicine and Science, serving as a Consultant in the Division of Medical Oncology within the Department of Oncology. She holds leadership positions as Chair of Practice Innovation and Platform at the Mayo Clinic Comprehensive Cancer Center and Medical Director of Care at Home at the Center for Digital Health. With expertise spanning clinical oncology, research, and digital health innovation, Dr. Haddad directs her efforts toward transforming cancer care delivery through technology-enabled solutions while maintaining an active clinical practice focused on breast cancer.

• MD from Creighton University School of Medicine (2001)
• Residency in Internal Medicine at Mayo Clinic College of Medicine and Science (2004)
• Fellowship in Hematology, Oncology and Transplantation at University of Minnesota (2007)

Dr. Haddad's research program centers on experimental therapeutics for breast cancer, particularly drug-resistant disease, with significant contributions to phase I/II clinical trial development and biomarker identification. Her work bridges traditional oncology with digital health innovation, exploring how connected health technologies and artificial intelligence can transform cancer care delivery. She has developed novel approaches to optimize endocrine therapy in breast cancer and has investigated mechanisms of resistance to targeted therapies. Her research extends to breast cancer survivorship, where she has pioneered technology-enabled models for post-treatment care.

With 99 published research outputs, Dr. Haddad's scholarly work demonstrates consistent productivity with 11 publications in 2024 alone. Her research spans clinical trials, molecular mechanisms of drug resistance, digital health applications, and breast cancer survivorship. She has led significant grant-funded projects including a Congressionally Directed Medical Research Programs award targeting fatty acid synthase in drug-resistant breast cancer and National Cancer Institute-funded research on Aurora-A kinase.

• Multiple 'Top Performer' awards from Mayo Clinic (2020, 2022, 2024, 2025)
• HIMSS Future50 Clinical Leader (2021)
• Innovation Award from Mayo Clinic Midwest Clinical Practice Committee (2019)
• Multiple Excellence in Teaching Awards (2013, 2014, 2018)
• Best Doctors recognition by Minnesota Monthly (2015)

Dr. Haddad mentors medical students, residents, and fellows while leading multiple research initiatives through her roles at the Mayo Clinic Comprehensive Cancer Center. She serves on the Health Care Delivery Scientific Program Committee of the American Society of Clinical Oncology and contributes to national efforts to transform cancer care delivery. Through her leadership in digital health innovation, she has developed remote patient monitoring programs and structured data capture systems that enhance cancer care quality and accessibility.

As Director of the Practice Innovation and Platform component at the Mayo Clinic Comprehensive Cancer Center, Dr. Haddad leads initiatives that integrate cutting-edge technology with clinical care, focusing on decentralized clinical trials, connected health solutions, and artificial intelligence applications in oncology. Her work bridges the gap between traditional cancer treatment and the digital future of healthcare delivery.