Tomas Strucko

Tomas Strucko is a researcher in the Department of Biotechnology and Biomedicine at the Technical University of Denmark (DTU), specializing in synthetic biology and metabolic engineering with a focus on yeast species including Saccharomyces cerevisiae and Komagataella phaffii. He develops advanced genetic tools for efficient strain engineering, particularly CRISPR-Cas systems.

• Academic employee at DTU
• Member of Synthetic Biology section

Research Interests:

• Design and optimization of microbial cell factories
• Development of CRISPR-based genome editing platforms
• Metabolic pathway engineering for chemical production
• High-throughput strain construction techniques
• Comparative yeast genetics
• Laboratory evolution for metabolic adaptation

Notable Contributions: Co-developed CRI-SPA (CRISPR-based strain production automation), created oligonucleotide-mediated editing systems for Komagataella phaffii, and pioneered gene amplification techniques through DNA repair mechanisms. His work has been cited 15 times across 5 publications in 2023-2024.

Students: Supervised PhD candidate Porcayo Loza in yeast-based algal biomass conversion projects.

Project Affiliations:

• Engineered yeast strains for bulk chemicals from algal biomass (2015-2022)
• Designer yeast library for metabolic engineering (2014-2016)
• Vanillin production cell factory development (2010-2014)