Tina Perica

Prof. Tina Perica is an Assistant Professor (tenure-track) in the Department of Biochemistry at the University of Zurich, joining in July 2021. Her research focuses on understanding how biochemical properties of proteins encode systems-level functions in signal transduction and gene regulation. Her lab integrates protein biochemistry, biophysics, functional genomics, and computational biology to study cellular regulation mechanisms.

Education:

• B.Sc. in Biology, University of Zagreb (2008)
• Ph.D. in Biochemistry, University of Cambridge (2013)
• Postdoctoral training at University of California, San Francisco (2013–2021)

Research Interests:

• Systems Biochemistry
• Allosteric Regulation in GTPases and Kinases
• Genotype-to-Phenotype Mapping
• Functional Genomics and Computational Biology

Her team explores how molecular mechanisms of proteins interact within cellular networks to regulate complex processes, aiming to predict therapeutic effects and disease mutations.

Lab Activities:

• Develops experimental and computational tools to map functional interactions in signaling pathways
• Focuses on targeted perturbations of proteins to study systems-level effects
• Emphasizes interdisciplinary approaches blending biochemistry with systems biology