Thomas Thekkumkara

Thomas Thekkumkara is Professor and Chair of Biomedical Sciences at Texas Tech University Health Sciences Center School of Pharmacy in Amarillo, Texas. He has been continuously employed at this institution since 2000, progressing from Associate Professor to Professor and ultimately to his current position as Chair of Biomedical Sciences since 2014.

Dr. Thekkumkara's research focuses on the molecular mechanisms of angiotensin receptor regulation, particularly the AT1 receptor, with significant contributions to understanding gene expression, receptor signaling, and cross-talk with other physiological systems. His work spans cardiovascular pharmacology, renal physiology, and blood-brain barrier transport mechanisms.

Analysis of his 15 most recent publications reveals a consistent research trajectory centered on angiotensin receptor biology, with expanding interests in G-protein coupled receptors, natural product pharmacology, and ischemia-reperfusion injury. His work demonstrates strong interdisciplinary connections between molecular biology, pharmacology, and physiology.

Dr. Thekkumkara has secured significant research funding through two major NIH grants:

• ROLE OF GLUCOSE IN hAT1 GENE EXPRESSION (R01DK072140) from the National Institute of Diabetes and Digestive and Kidney Diseases (2006-2012)
• 3UTR DETERMINANTS IN ANGIOTENSIN II RECEPTOR REGULATION (R01HL061356) from the National Heart, Lung, and Blood Institute (1999-2005)

These grants supported his laboratory's work on angiotensin receptor regulation and gene expression for over 13 years.

His research has been conducted in collaboration with numerous colleagues across multiple institutions, with frequent co-authorship patterns suggesting stable research teams focused on receptor biology and pharmacology. While specific laboratory structure isn't detailed in the available information, the consistent publication record indicates an active research group.