Thomas Nägele

Prof. Thomas Nägele is a Group Leader at the Department of Biology I, Ludwig-Maximilians-Universität München. His research focuses on plant metabolism, particularly cold and temperature acclimation, stress responses, and systems biology approaches. His work integrates metabolomics, mathematical modeling, and subcellular analysis to understand metabolic regulation in plants under environmental changes.

Key research areas include the role of chloroplast positioning in immunity, carbohydrate metabolism dynamics, and the molecular mechanisms underlying plant adaptation to abiotic stresses. He has pioneered methods like the Dark-Root device for non-invasive root analysis and developed computational tools such as MInfer for metabolomic network analysis.

His contributions span plant cold acclimation, heat tolerance, CO₂ effects, and flavonoid metabolism. He emphasizes interdisciplinary approaches, combining experimental and computational methods to address complex biological questions in plant-environment interactions.

Notable achievements include defining metabolic core modules of stress response and elucidating the role of SnRK1 kinase in energy signaling. His research bridges basic science with potential applications in crop resilience under climate change.