معرفی
Thomas Marjot is an NIHR Academic Clinical Lecturer in Hepatology at the University of Oxford and a Gastroenterology and Hepatology Specialist Registrar at Oxford University Hospitals. He maintains key affiliations with the Translational Gastroenterology and Liver Unit (TGLU), Oxford Centre for Diabetes Endocrinology and Metabolism (OCDEM), and Sir Jules Thorn Sleep and Circadian Neuroscience Institute (SCNi). He serves as Young Investigator representative for the European Association for the Study of the Liver (EASL) and participates in the EASL Artificial Intelligence Taskforce.
His academic foundation includes graduation from Imperial College London (2012) and completion of a DPhil in 2023 during a Wellcome Trust Clinical Research Training Fellowship. His research methodology integrates insulin infusion studies, stable isotope assessments of glucose/lipid handling, and multi-omics tissue biopsy analysis.
Dr. Marjot's primary research explores metabolic pathways in MASLD, hepatic/adipose/muscle insulin sensitivity, circadian regulation of human metabolism, and sleep-wake disturbances in cirrhosis/hepatic encephalopathy patients. He investigates shift-worker health impacts, diurnal metabolic patterns, chronopharmacology, and SARS-CoV-2 liver involvement using wearable technology for behavioral rhythm assessment.
His publication trajectory demonstrates increasing focus on circadian-metabolic intersections, highlighted by his 2024 Journal of Hepatology article on heart-liver cross-disease communication, indicating expansion into multi-organ metabolic interactions and translational applications of circadian science.
His major scientific recognitions include:
- British Association for the Study of the Liver (BASL) Andy Burroughs Young Investigator of the Year (2022)
- British Society of Gastroenterology (BSG) Young Gastroenterologist of the Year – Clinical and Translational Science (2022)
Mentored by Professors Jeremy Tomlinson, David Ray, Leanne Hodson, and Ellie Barnes, he prepares to assume an academic and teaching role as Sara Hope Browne Research Associate at Jesus College Oxford from October 2024. His research integrates clinical hepatology with metabolic and circadian neuroscience through institutional collaborations.
His work operates within the collaborative ecosystem of TGLU, OCDEM, and SCNi, combining clinical hepatology expertise with metabolic physiology and circadian neuroscience to address complex liver disease mechanisms through interdisciplinary experimental medicine approaches.
