معرفی
Thomas J. Magliery is an Associate Professor in the Department of Chemistry & Biochemistry at The Ohio State University. He holds roles as Vice Chair for Graduate Studies, co-director of the NIH T32 Molecular Biophysics Training Program, and faculty director of the Ohio Five-OSU Summer Undergraduate Research Experience. He is also the Chief Scientific Officer of Enlyton, Ltd., a biotechnology startup.
Education includes an A.B. in Chemistry from Kenyon College, a Ph.D. from UC Berkeley, and an MBA from Ohio State. His postdoctoral work at Yale focused on helical protein redesign.
Research focuses on understanding protein stability via combinatorial and statistical approaches, with applications in therapeutic protein engineering. Key projects include improving enzyme activity against organophosphorus agents, developing antibody fragments for cancer targeting, and exploring Notch signaling for immunomodulation. His lab uses techniques like High-Throughput Thermal Scanning (HTTS), NMR, and X-ray crystallography.
Funding comes from NIH grants, including NIGMS and NINDS's CounterACT program. Recent students have pursued postdocs at Scripps Florida and UT Austin, while undergraduates have gone to top graduate programs and medical schools.
Labs and collaborations include the Magliery Lab at Ohio State, partnerships with the U.S. Army Medical Research Institute, and industry ties through Enlyton, Ltd.
