Thomas E. Wilson

Thomas E. Wilson is a Professor in the Department of Pathology and Human Genetics at the University of Michigan Medical School. His work bridges clinical practice and research, focusing on molecular genetics, chromosomal instability, and bioinformatics.

Dr. Wilson leads educational initiatives, including directing classes and research projects through the Undergraduate Research Opportunity Program (UROP), fostering diverse trainees in translational research and genomic technologies. Though his formal education details (MD, PhD) are noted, his mentorship efforts emphasize data standardization and tool-sharing in bioinformatics.

His research spans three core areas:

• Genomic Instability & DNA Repair in yeast and mammalian systems, including POLQ-mediated structural variants and replication stress mechanisms.
• Spatial Transcriptomics via innovations like Seq-Scope, which repurposes Illumina flow cells for high-resolution gene expression mapping.
• HIV/AIDS Public Health examining treatment adherence, stigma dynamics, and substance use intersections in women’s health outcomes.

Recent publications highlight:

• Structural variation analysis in replication stress models
• Development of error-minimized sequencing protocols
• HIV reservoir genetics and social determinants of ART adherence

Dr. Wilson contributes to both technical innovation and clinical/public health research, maintaining active laboratory investigations and educational leadership.