Thazin Nwe Aung

Dr. Thazin Nwe Aung is an Associate Research Scientist in the Department of Pathology at Yale School of Medicine, specializing in cancer biomarker research using spatial multi-omics and computational biology. She holds a PhD in Genetics from the University of Adelaide and has conducted postdoctoral research at Yale since 2019. Her work focuses on identifying biomarkers predictive of treatment response in cancers like triple-negative breast cancer (TNBC) and head and neck cancer, leveraging spatial context in tissue architecture.

• Education:
• PhD in Genetics, Genomics, and Evolution, University of Adelaide (2019)
• MS in Biotechnology/Molecular Genetics, Yangon Technological University (2006)
• BS (Honors) in Biotechnology/Molecular Genetics, Yangon Technological University (2004)

Research Interests: Dr. Aung’s research integrates spatial biology, machine learning, and systems biology to uncover mechanisms of drug resistance and immunotherapy response. Her key areas include:

• Biomarker development for TNBC and head and neck cancer
• Spatially resolved gene signatures for immunotherapy outcomes
• Quantitative analysis of tumor microenvironment interactions

Publications Trends: Recent work emphasizes spatial profiling of biomarkers like BCAM, LAIR-1, and ribosomal RNAs to predict treatment resistance. Key contributions include identifying immune cell infiltration patterns linked to exceptional responses in head and neck cancer.

Awards/Grants: Notable funding includes Patterson Mentored Research Award ($200K), Susan Love Fund Award ($100K), and Lion Heart Foundation grants for breast cancer research. Recognized in AACR25 for contributions to spatial biomarker development.

Lab/Teams: Leads projects in the Rimm Lab, collaborating with experts like David Rimm and Barbara Burtness. Active in translational oncology and immunotherapy biomarker initiatives.