معرفی
Tayyaba Ishaq is a Research Fellow in the Department of Internal Medicine at Yale School of Medicine. Her work focuses on genetics of skeletal disorders, protein purification for therapeutic applications, and chronic kidney disease (CKD) research. She is affiliated with the Braddock Lab, where she investigates ENPP1 enzyme regulation, DNase1 production, and MPO antigen development. Her research also includes studying skeletal dysplasia variants and CKD murine models.
Education:
- MPhil in Human Genetics, University of the Punjab, Lahore, Pakistan (2017)
- BS in Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan (2015)
Research Interests: Tayyaba’s research spans genetics-driven bone disorders, protein purification techniques, and environmental microbiology. Her recent studies have explored KIF24 and GNPNAT1 gene variants linked to skeletal dysplasia, as well as biofilm formation in water systems. She applies biochemical methods to understand ectopic calcification and bone mineralization pathways.
Publications: Her work has been published in journals like Journal of Bone and Mineral Research and Journal of Medical Genetics, highlighting contributions to skeletal disorder genetics and protein-based therapies.
Labs/Teams: She contributes to the Braddock Lab, focusing on translational research in bone biology and CKD pathophysiology.
