معرفی
Tanyeri Barak is an Assistant Professor of Neurosurgery at the Yale School of Medicine, Yale University. He completed his MD at Istanbul University (2011) and joined the Gunel Lab in 2013 for postdoctoral research. His work focuses on gene discovery in cerebrovascular disorders, using zebrafish, Xenopus, and mouse models. Key contributions include identifying roles for LAMC3, NDE1, and WDR62 in brain development and microcephaly. He studies endothelial and smooth muscle cell remodeling in aneurysms and uses spatial transcriptomics. His research has been published in Nature Medicine, Nature Genetics, and Neurology.
Education: MD from Istanbul University (2011). Postdoc at Yale Gunel Lab (2013–2015), current role as Associate Research Scientist (2015–present).
Research interests center on molecular mechanisms of cerebrovascular diseases, including intracranial aneurysms and vein of Galen malformations. He explores genetic and immunological factors in meningiomas, with notable work on TRAF7 mutations and mTOR signaling. His lab uses advanced techniques like scRNA-seq and spatial transcriptomics.
Publications highlight his focus on genomic profiling of tumors, immune dynamics in aneurysms, and gene discovery in developmental disorders. Awards include the 2021 AANS/CNS Cerebrovascular Section Best Clinical Scientific Paper Award.
Collaborators include Murat Günel, Ketu Mishra-Gorur, and Danielle Miyagishima. His work bridges basic science and clinical neurosurgery, emphasizing translational research.