معرفی
Swathi Yadlapalli is an Assistant Professor in the Department of Cell and Developmental Biology at the University of Michigan. Her research focuses on understanding the neural and molecular mechanisms underlying circadian clock function and their role in human pathologies caused by circadian disruption. The Yadlapalli Lab employs advanced techniques like CRISPR-based gene tagging, biocalorimetry, and single-molecule RNA-FISH to study circadian rhythms in model organisms such as Drosophila melanogaster and C. elegans.
Her research interests span circadian biology, chromatin dynamics, temperature sensing in circadian systems, and the interplay between metabolic activity and circadian regulation. Recent work highlights roles for clock proteins, nuclear bodies, and p-bodies in maintaining circadian rhythms, alongside innovations in microfluidic and calorimetric tools for real-time metabolic monitoring.
Dr. Yadlapalli's contributions bridge molecular biology, genetics, and engineering to unravel how circadian clocks integrate environmental cues like temperature to regulate behavior and physiology. Her lab’s techniques have advanced the study of spatiotemporal organization of clock complexes and their post-translational regulation.
No scientific awards or grants are explicitly listed in the provided information. Current research efforts emphasize translational applications of circadian biology to understand sleep disorders, metabolic diseases, and neurodegenerative conditions rooted in circadian disruption.
