جستجوی استاد راهنمای دانشگاهی

Nicole C. Riddle is a Professor and Associate Chair for Research and Facilities in the Department of Biology at the University of Alabama at Birmingham (UAB). She holds a B.S. in Biology from the University of Missouri Columbia and a Ph.D. in Evolutionary and Population Biology from Washington University in St. Louis. Her research focuses on epigenetics and chromatin dynamics, particularly in the context of aging and sex differences using Drosophila melanogaster as a model system. Dr. Riddle's work explores how epigenetic mechanisms influence lifespan, genome stability, and phenotypic variation. She has pioneered the use of Drosophila to study exercise-induced physiological changes and their genetic underpinnings. Her lab investigates the roles of HP1 proteins in transcriptional regulation and chromatin organization, with recent studies emphasizing cross-species comparisons of aging mechanisms. Her research has been supported by grants including the BII: IISAGE project on sex-specific aging mechanisms. Notable contributions include developing novel tools like the Rotating Exercise Quantification System (REQS) to measure Drosophila activity levels. Dr. Riddle actively mentors students and postdoctoral researchers, inviting inquiries via riddlenc@uab.edu to join her lab.

• Epigenetics
• Chromatin Structure
• Drosophila melanogaster
• +۳ مورد دیگر

David Walker is a Professor and Vice Chair of Academic Personnel in the Department of Integrative Biology and Physiology at the University of California, Los Angeles. He leads a research lab focused on understanding the molecular and cellular basis of aging, utilizing Drosophila melanogaster to investigate mechanisms such as mitochondrial dysfunction, autophagy, and intestinal barrier integrity. His work aims to identify therapeutic targets for age-related diseases. Education: B.S., Genetics, Queen's University Belfast (1995) MRes, Molecular Biology, University of Manchester (1996) Ph.D., Genetics, University of Manchester (2000) Walker's research interests center on the biological processes driving aging, with emphasis on mitochondrial dynamics, neurodegeneration, and gut-microbiota interactions. His lab employs genetic, molecular, and physiological approaches in Drosophila to dissect how cellular deterioration impacts lifespan and healthspan, bridging insights to human aging pathologies. Key themes include the role of autophagy adaptors (e.g., p62/SQSTM1), mitochondrial fission, and intestinal homeostasis in longevity. His recent publications (2014–2024) reveal a consistent focus on brain aging, mitophagy, and gut-brain axis disruptions, with trends toward identifying midlife interventions for healthspan extension. Articles frequently integrate cellular stress responses, metabolic regulation, and neurodegeneration, highlighting Drosophila as a versatile model for translational aging research. No scientific awards, prizes, or fellowships are mentioned in the provided text. While specific grants or student advisees are not detailed, Walker's lab actively mentors researchers and contributes to collaborative projects on aging mechanisms. Future directions may involve exploring mitochondrial-immune interactions and novel longevity pathways. Walker directs a Drosophila-focused laboratory at UCLA, emphasizing genetic screens and mechanistic studies to uncover evolutionarily conserved aging pathways. The team investigates tissue-specific aging cascades, including neuronal and intestinal systems, to develop strategies for mitigating age-related decline.

• Aging
• Mitochondrial Biology
• Neurodegeneration
• +۳ مورد دیگر

Dr. Tristan A.F. Long is an Associate Professor in the Department of Biology at Wilfrid Laurier University's Faculty of Science in Waterloo, Ontario. A behavioral ecologist and evolutionary geneticist, he focuses on sexual selection and the role of female mate preference variation in evolutionary change. With teaching responsibilities for large introductory biology courses like BI111 and BI393, he has developed innovative active learning techniques using playing cards, iClickers, and role-playing games to teach population genetics and ecological principles. University of Western Ontario - BSc in Honours Ecology and Evolution (1999) University of Guelph - MSc in Zoology (2001) Queen’s University - PhD in Biology (2005) University of California Santa Barbara - Postdoctoral Fellow (2005-2009) University of Toronto - Postdoctoral Fellow (2009-2010) His research examines how female Drosophila melanogaster vary in their mating preferences and how these differences shape evolutionary trajectories. He has published extensively on reproductive plasticity, sexual conflict, and environmental interaction effects. His laboratory combines experimental evolution with computational modeling to explore genetic trade-offs and behavioral adaptations. Scientific awards include the Laurier Teaching Award for Sustained Excellence (2017). He has developed innovative classroom techniques like the Battle of the Beaks exercise for teaching adaptive evolution and an iClicker-based population genetics simulation using playing cards. His 2024 BI393 biostatistics course policy strongly discourages generative AI use due to concerns about educational integrity and environmental impact.

• Evolutionary genetics
• Behavioral ecology
• Experimental evolution
• +۳ مورد دیگر

Professor Ralf Stanewsky leads the Stanewsky Group at the Institute of Neuro- and Behavioral Biology, University of Münster. His research focuses on the molecular mechanisms of circadian rhythms in Drosophila melanogaster , particularly how environmental cues like light and temperature reset the circadian clock. The group employs genetic, molecular, histological, and behavioral approaches to study sensory pathways and their integration in central clock neurons. Member of the Multiscale Imaging Centre (MIC) and Imaging Network – Microscopy Current lab members: Ph.D. students Anna Katharina Eick, Angelica Coculla, Maia Zabel Barroso Technical assistants Regina Hube and Ume Aiman Research Themes Light and temperature synchronization of circadian clocks Temperature compensation mechanisms in biological timing Neuronal integration of environmental signals Evolutionary aspects of circadian regulation Professor Stanewsky’s work spans molecular clock components (e.g., cryptochromes, timeless gene variants) to broader ecological implications of temporal niche choice. His lab investigates how clock gene expression responds to seasonal changes and environmental stressors, while also exploring novel synchronization pathways beyond classical photoreceptors. Publication Trends Recent articles emphasize temperature-dependent clock regulation , evolutionary capacitance via Hsp90 , and non-canonical phototransduction in circadian systems. Key subfields include nuclear transport dynamics, kinase evolution, and computational modeling of periodic patterns across species. Contact Information Institute of Neuro- and Behavioral Biology, University of Münster MIC | Röntgenstraße 16, D-48149 Münster, Germany Email: stanewsky@uni-muenster.de Phone: +49 251 8321029

• Circadian Rhythms
• Biological Clocks
• Neurobiology
• +۳ مورد دیگر

Sophie Caron is an Associate Professor in the Department of Biological Sciences at the University of Utah, where she leads a research laboratory investigating fundamental mechanisms of brain function using Drosophila melanogaster as a model system. Her work focuses on how the brain generates internal representations of the external world, stores memories, and translates these into behavior through multisensory integration. Education: B.S. from Université de Montréal Ph.D. from New York University Dr. Caron's research centers on the Drosophila mushroom body—a critical brain center for learning and memory—with emphasis on multisensory integration mechanisms. Her lab investigates how the brain combines information from multiple sensory modalities (olfaction, vision, etc.) to form unified percepts, challenging traditional views of sensory processing. Key discoveries include the demonstration that mushroom body connectivity follows near-random patterns that maximize memory capacity, and the identification of cross-modal sensory pathways beyond olfaction. Current work explores evolutionary adaptations in neural circuits across Drosophila species and developmental mechanisms establishing sensory wiring. Analysis of her 15 most recent publications (2019-2024) reveals three dominant research trajectories: (1) high-resolution mapping of Kenyon cell inputs using advanced techniques like dye electroporation, (2) computational modeling of how connectivity patterns shape sensory representation and learning, and (3) evolutionary studies of circuit architecture across Drosophila species. Her work consistently bridges experimental neuroanatomy with theoretical frameworks, emphasizing the interplay between random and structured wiring principles in neural circuit design. Scientific Awards: NSF CAREER Award (2021) for research on brain size evolution and neuronal circuit adaptation Dr. Caron mentors graduate students in the University of Utah's Molecular Biology Program and directs an active laboratory utilizing genetic, imaging, and behavioral approaches. Her research program is supported by competitive grants including the NSF CAREER award, with collaborations spanning neuroscience and evolutionary biology. Current projects investigate multisensory integration mechanisms, evolutionary drivers of neural circuit specialization, and developmental basis of sensory wiring. The Caron Lab maintains specialized facilities for Drosophila neurogenetics, advanced microscopy, and behavioral analysis. Her team collaborates with the University of Utah's Brain Institute and Center for Cell and Genome Science, contributing to interdisciplinary initiatives in neural circuit mapping and evolutionary neuroscience. Ongoing work explores how sensory representations evolve in response to ecological pressures and how circuit architecture enables flexible behavior in complex environments.

• Neuroscience
• Neurobiology
• Sensory Systems
• +۵ مورد دیگر

Wilfried Haerty is a Senior Group Leader in Evolutionary Genomics at the University of East Anglia (UEA), affiliated with the School of Biological Sciences and the Norwich Institute for Healthy Aging. He also holds an external position as Senior Group Leader at the Earlham Institute since December 2015, reflecting his significant role in genomics research. Institution: University of East Anglia School: School of Biological Sciences External Affiliation: Earlham Institute Position: Senior Group Leader His academic background includes a Doctor of Science from Université de Paris, awarded in 2004, based on research into reproductive isolation in Drosophila melanogaster . Dr. Haerty's research focuses on evolutionary and comparative genomics, particularly the characterization of functional non-coding sequences and long non-coding RNAs in mammalian and human genomes. He investigates evolutionary constraints and selection pressures using population-level sequence variation data. His work integrates computational and genomic approaches to understand genome evolution across species. The recent trends in his publications highlight a strong focus on genome evolution, including hybridization in cichlid fishes, NUMT dynamics in mammals, fission yeast phylogenetics, avian developmental genomics, and evolutionary behavioral responses. These reflect interdisciplinary research spanning molecular evolution, genomics, developmental biology, and ecology. No scientific awards are explicitly mentioned in the provided text. There is no mention of student advising or research grants in the available information. However, his leadership role as a Group Leader suggests involvement in mentoring researchers and managing research projects. His collaborations span multiple institutions and countries, as indicated by co-authorship on recent studies. Dr. Haerty is associated with research teams at both the University of East Anglia and the Earlham Institute, particularly within genomics and evolutionary biology groups. His work is part of broader collaborative networks in evolutionary genomics and healthy aging, including the Norwich Institute for Healthy Aging.

• Evolutionary Genomics
• Comparative Genomics
• Functional Non-Coding Sequences
• +۷ مورد دیگر

Sudhir Kumar is a Professor and Principal Investigator at Temple University, leading a research laboratory focused on molecular evolution, phylomedicine, and functional genomics. His lab develops mathematical methods, computational algorithms, and software packages for analyzing genomic variation across populations, pathogens, tumors, and species. Key contributions include the widely used MEGA software (www.megasoftware.net) for molecular evolutionary analysis and the TimeTree knowledge-base (www.timetree.org) that synthesizes evolutionary knowledge on species divergence times. Dr. Kumar's research interests center on integrating mathematical and computational techniques into evolutionary biology and biomedicine. His lab pursues a holistic paradigm where evolutionary and genomic patterns are discovered through comparative analysis of big datasets, then used to reveal underlying biological processes and develop predictive models. His work spans phylomedicine of genetic diseases, molecular phylogenomics, and the timetree of life, with recent innovations including Bayesian methods, machine learning algorithms, and statistical approaches for inferring molecular phylogenies, divergence times, and pathogenic mutations. Analysis of his recent publications reveals a strong trend toward applying artificial intelligence and machine learning to evolutionary genetics, with multiple 2025 papers focused on sparse learning techniques, transformer-based models, and AI-assisted analytical protocols. His work increasingly bridges evolutionary biology with cancer genomics and precision medicine applications. His scientific achievements have been recognized with the prestigious 2025 George W. Beadle Award from the Genetics Society of America, which honors his "efforts to democratize evolutionary genetics." Dr. Kumar has mentored numerous doctoral candidates, postdoctoral researchers, and graduate students, many of whom have gone on to faculty positions at institutions including Oakland University and universities in Brazil. His lab includes current doctoral candidates working in bioinformatics and statistical molecular evolution, supported by technical staff including programmers, genome tech specialists, and informatics specialists. The Kumar Laboratory operates as an interdisciplinary research hub with multiple projects including MEGA (Molecular Evolutionary Genetics Analysis), TimeTree, myPEG (web-based evolutionary tools), and FlyExpress (a knowledge base for Drosophila melanogaster embryo images). The lab emphasizes green computing efforts aimed at democratizing scientific practice and making big data analytics more accessible.

• Molecular Evolution
• Phylomedicine
• Functional Genomics
• +۵ مورد دیگر

Marta Moita is a Research Professor and Principal Investigator at the Champalimaud Foundation's Champalimaud Research center in Lisbon, Portugal, where she leads the Moita Lab in the Behavioral Neuroscience research group. Her laboratory investigates the neural and behavioral mechanisms underlying threat responses in animals, with particular focus on how contextual cues influence defensive decision-making between freezing and fleeing behaviors. Dr. Moita's research spans multiple levels of analysis, from collective behavior in social contexts to detailed neural mechanisms. Her lab employs diverse model organisms, particularly fruit flies ( Drosophila melanogaster ) and rats, to study how animals integrate social, spatial, and internal state information to guide threat responses. Key research areas include fear conditioning, emotional contagion, social safety cues, and the neural circuits underlying defensive behaviors. Her work often bridges behavioral neuroscience with evolutionary biology perspectives, examining how defensive strategies have been shaped by natural selection. The Moita Lab's publication record demonstrates a consistent focus on innovative approaches to understanding threat processing across species. Recent work has revealed how looming visual stimuli drive defensive responses in rats, how social cues can override threat levels, and the physiological consequences of threat exposure. The lab frequently publishes in high-impact journals including Current Biology , Nature Communications , and Science Reports , reflecting the significance of their contributions to the field. Dr. Moita actively mentors several PhD and Masters students, including Charlotte Rosher, Violetta La Franca, Mariana Franco, Matilde Henriques, and Mirjam Heinemans. Her laboratory team also includes postdoctoral researchers like Alexandre Leitão, Anna Hobbiss, and Ricardo Neto Silva, along with research technicians and lab administrators who support the diverse research projects.

• Behavioral Neuroscience
• Fear Conditioning
• Animal Behavior
• +۵ مورد دیگر

Prof. Dr. Kei Ito is a leading neuroscientist at the University of Cologne , specializing in Drosophila melanogaster brain architecture. His research focuses on mapping " terra incognita " regions of the brain, analyzing glial cell functions across development, and establishing standardized insect brain nomenclature through international collaboration. As AXA Chairholder and former HHMI Senior Fellow , he combines molecular genetics with 3D virtual reality visualization to unravel neuronal network organization . Academic Affiliation : University of Cologne (2016–present) Prior Positions : The University of Tokyo (2002–2017), National Institute for Basic Biology (1998–2002) Research Interests span multiple domains: "Terra Incognita" Analysis : Systematic mapping of previously uncharacterized brain regions (70% of brain volume) Glial Cell Biology : Classification and functional analysis from embryo to adult Connectome Research : Integration of electron microscopy data with genetic tools Neuronal Lineage Studies : 3D reconstruction of neuroblast progeny patterns Scientific Contributions include: Creation of 4,500 NP Gal4 driver lines (Japan consortium, 1998) Pioneering Split-Gal4 systems for precise neuron labeling Establishment of 6 distinct neuron naming schemes for EM data Leadership in Insect Brain Name Working Group (2007–2014) Advising Legacy features direct mentorship of 6 doctoral students and collaborative analysis of 3,777 neuron types in EM datasets. His lab maintains 1,000+ specific Split-Gal4 lines for terra incognita research.

• Neuroscience
• Drosophila Brain Architecture
• Glial Cell Biology
• +۴ مورد دیگر

Dr. Marta Zlatic is a Principal Research Associate at the Department of Zoology , part of the School of Biological Sciences at the University of Cambridge. She leads the Zlatic Lab, focusing on the structural and functional relationships within neural circuits. Her research explores how nervous systems integrate sensory information and prior experiences to enable decision-making, emphasizing learning and memory , sensorimotor transformations , and connectomics . Using Drosophila melanogaster larvae as a model organism, her work combines optogenetics , electron microscopy , and functional imaging to decode circuit principles. Recent publications highlight trends in connectome analysis and behavioural neuroscience , with subfields spanning synaptic architecture , neural network modeling , and genetic manipulation techniques . She collaborates with interdisciplinary teams and maintains active research partnerships at the MRC Laboratory of Molecular Biology. Group members include Bernd Breuer, Nicolo Ceffa, Michael Clayton, and other researchers advancing understanding of Drosophila neurobiology. The lab contributes to Cambridge's Athena Swan Bronze Award initiatives for equality and inclusion in research environments.

• Systems neuroscience
• Circuit mechanisms of behaviour
• Learning and memory
• +۲ مورد دیگر

Prof. Dr. Christian Ungermann is a Professor in the Department of Biochemistry at the University of Osnabrück, Germany. His research focuses on the molecular mechanisms underlying endosome, lysosome, and autophagosome biogenesis. He combines cell biological methods with in vitro reconstitution assays to study protein complexes involved in these processes. His work is critical for understanding disease-related mechanisms linked to organelle dysfunction. Research topics include endosomal maturation, autophagosome/lysosome biogenesis, and endosomal signal transduction. Model systems include Saccharomyces cerevisiae, insect cells, and Drosophila melanogaster. Key methods are protein purification, fluorescence microscopy, membrane fusion assays, and enzymatic activity assays. Recent publications highlight studies on Rab GTPase regulation, endosomal Rab transitions, and CORVET tethering complex structure, reflecting expertise in membrane trafficking and organelle dynamics.

• Molecular Biology
• Cell Biology
• Autophagy
• +۳ مورد دیگر

Dr. Paul Marcogliese is an Assistant Professor in the Department of Biochemistry & Medical Genetics at the University of Manitoba’s Max Rady College of Medicine. He leads the Marcogliese Lab, focused on understanding the molecular and cellular mechanisms underlying neurological disorders such as autism, Parkinson’s disease, and rare conditions like NEDAMSS. His work employs Drosophila melanogaster and mouse models to assess genetic variants and develop therapeutic strategies. Dr. Marcogliese holds a PhD in Neuroscience from the University of Ottawa and completed postdoctoral training at Baylor College of Medicine, where he studied neurodegenerative disease mechanisms. His research integrates functional genomics, disease modeling, and drug screening to identify genetic drivers of neurological disorders and potential treatments. Key research interests include: Functional assessment of human disease variants using Drosophila and murine models Role of Wnt signaling in neurodegeneration and neurodevelopmental disorders Identification of novel therapeutic targets for rare and common neurological conditions Dr. Marcogliese is affiliated with the Children’s Hospital Research Institute of Manitoba (CHRIM) and co-leads the ENRRICH and MGM research groups. He currently accepts Master’s and PhD students. His lab has secured grants from Brain Canada and the Manitoba Medical Service Foundation, among others. Recent achievements include the 2023 Shaun Lamoureux Legacy Award for grant writing and the 2024 Brain Canada Future Leaders award. His work has been published in Genome , Neurobiology of Disease , and other high-impact journals.

• Neurological Disease Mechanisms
• Molecular Genetics
• Functional Genomics
• +۷ مورد دیگر

Barbara Mellone is a Professor in the Department of Molecular and Cell Biology / Genetics and Genomics at the University of Connecticut. She leads the Mellone Lab, which focuses on understanding how genetic information is accurately passed from one cell generation to the next through the study of centromeres. Her research interests include: Centromere biology and function Chromosome segregation mechanisms Genetic and epigenetic regulation of centromeres Evolution of centromeres across species Using Drosophila melanogaster as a model system for chromosome studies Connections between chromosome segregation errors and human diseases like cancer Professor Mellone's recent publications demonstrate a strong focus on centromere structure and function, particularly examining CENP-A chromatin, centromere assembly factors like CAL1, and the evolutionary aspects of centromere biology. Her work combines genetic, molecular, and evolutionary approaches to unravel the fundamental mechanisms of chromosome inheritance. Her laboratory has made significant contributions to understanding how centromeres are built, maintained, and evolve, with implications for human diseases associated with chromosome segregation errors.

• Centromere Biology
• Chromosome Segregation
• Genetics
• +۴ مورد دیگر

Aparna Ratheesh serves as an Associate Professor at the Centre for Mechanochemical Cell Biology at the University of Warwick, where she leads research in the Wellcome-Warwick Quantitative Biomedicine Programme. Her work bridges cell biology, developmental biology, and biophysics, focusing on the mechanical and biochemical interactions that govern cell migration in living organisms. Dr. Ratheesh's research centers on cell migration through complex tissue barriers, a process essential for embryonic development, immune homeostasis, and pathological conditions like cancer metastasis. Her lab utilizes Drosophila melanogaster macrophages during embryonic development as a model system, leveraging the genetic tractability of fruit flies combined with quantitative live imaging, biophysical tools, and mathematical modeling. Current research focuses on how macrophages sense tissue stiffness and alter their force-generating machinery for migration, and how macrophage-generated forces affect surrounding tissue mechanics, cell fate, and positioning. Analysis of her publication record reveals a consistent focus on cellular mechanobiology, with particular emphasis on cell migration, tissue mechanics, and immune cell behavior. Her work spans both fundamental cell biological mechanisms and their implications for understanding disease processes, particularly in inflammation and cancer. The publications demonstrate a progression from basic molecular mechanisms of cell adhesion to more complex tissue-level mechanical interactions. Dr. Ratheesh maintains an active research program investigating the mechanical dialogue between migrating cells and their environment. Her work combines advanced imaging techniques with genetic manipulation in the Drosophila model system to address fundamental questions about how cells navigate through complex tissues during development and disease processes.

• Cell Migration
• Developmental Biology
• Mechanobiology
• +۴ مورد دیگر

Matthew Ronshaugen is a Senior Lecturer in the Division of Developmental Biology & Medicine (L5) at the Faculty of Life Sciences, University of Manchester. He has held academic positions since 2007 as a Manchester Fellow, followed by Lecturer (2012-2017), and Senior Lecturer since 2017. 1991-1995: Bachelor of Arts in Philosophy and Linguistics, University of Nevada, Las Vegas 1995-1997: Master of Science in Systematics, University of Nevada, Las Vegas 1997-2002: Doctor of Philosophy in Cell and Molecular Biology, University of California, San Diego 2003-2007: Ruth L. Kirschstein NIH Postdoctoral Fellow at University of California, Berkeley His research focuses on non-coding RNAs (ncRNAs), particularly their roles in gene expression and developmental differentiation. His lab investigates how ncRNA evolution contributes to metazoan body plan diversification, centering on the Hox complex—a conserved genomic region rich in ncRNAs. He uses tiling microarrays and fluorescent in situ hybridization to analyze ncRNA dynamics in Drosophila, Tribolium, and Parhyale. Recent publications highlight his work on miRNA functions in embryonic development, aging-related changes in myeloid cells, and comparative transcriptomics across arthropods. His team employs genetics tools to dissect ncRNA roles in transcriptional regulation, epigenetic control, and silencing mechanisms. Scientific Awards: Ruth L. Kirschstein NIH Postdoctoral Fellow Manchester Fellow He supervises research on developmental transcriptomes and contributes to datasets on piRNA expression and Hox complex analysis. Collaborations span immunology, genomics, and evolutionary development, with outputs cited in fields like RNA interference, transgenics, and wound healing.

• Non-coding RNA
• Gene Expression
• Developmental Biology
• +۶ مورد دیگر