معرفی
Suyin Pan is a researcher at the University of Southampton specializing in Medicinal Chemistry and Chemical Biology. His work focuses on targeted covalent inhibition and development of small molecule therapeutics for cancer, particularly addressing mutations like p53-Y220C.
Research Interests
- Targeted covalent inhibition mechanisms
- Structure-based drug design
- Protein-ligand interactions for oncology targets
- Development of non-acrylamide warheads in drug discovery
Recent Publication Trends
His 2024 work explores alternative warheads (2-sulfonylpyrimidines) to replace acrylamides in BTK inhibition, while his 2022 thesis focused on stabilizing the p53-Y220C mutant protein through small molecule ligands. These studies reflect interests in precision oncology and innovative chemical scaffolds.
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