Sundeep Keswani

Dr. Sundeep Keswani is a Professor of Surgery at Baylor College of Medicine, where he leads the Regenerative Tissue Repair Laboratory. His research focuses on molecular mechanisms of fetal wound healing and development of scarless tissue repair therapies, with significant work in congenital anomalies like diaphragmatic hernia and subaortic stenosis.

• Academic Appointments: Chief, Division of Pediatric Surgery
• Research Themes: Mechanotransduction, Extracellular Matrix, Immunomodulation

The lab investigates crosstalk between extracellular microenvironment, immune regulation, and mechanical forces in tissue repair outcomes. Recent publications emphasize:

• Shear stress effects on endothelial/macrophage responses
• Role of IL-10 in fibroblast signaling
• 3D modeling of congenital heart defects
• Nutritional optimization in neonatal ECMO
• Fetal surgical techniques for lung malformations

Dr. Keswani mentors Emily Steen and collaborates with Swathi Balaji. His team develops novel in vitro systems and computational models for congenital anomalies.