معرفی
Sumana Sharma is a Wellcome Career Development Fellow and Group Leader at the MRC Weatherall Institute of Molecular Medicine (University of Oxford). Her research focuses on T-cell signaling and next-generation immunotherapy design, particularly through inhibitory receptor signaling manipulation.
- PhD in genetic screening (Wellcome Sanger Institute, University of Cambridge)
- Postdoc in computational analysis (EMBL-EBI, Cambridge)
- Former Sir Henry Wellcome Postdoctoral Fellow (MRC-TIDU, Oxford)
Her work integrates CRISPR-based functional genomics, omics technologies, and primary T-cell editing to uncover regulatory mechanisms in immune suppression. Key contributions include developing CEN-tools for cancer gene analysis and creating high-throughput assays for T-cell signaling.
Recent publications span 2025-2015, emphasizing T-cell antigen detection, inhibitory signaling, and transcriptional reprogramming. Her research trends combine structural immunology, computational genomics, and therapeutic engineering.
- Wellcome Career Development Award
- Sir Henry Wellcome Postdoctoral Fellowship
Her lab uses multidisciplinary approaches to study immune regulation in cancer and chronic infections, with potential applications in autoimmune disease and tumor immunotherapy.
