Suman Dutta

Suman Dutta, M.Sc., Ph.D., is a Researcher at the Nuffield Department of Clinical Neurosciences (NDCN) at the University of Oxford, where he leads research in the Molecular Neurodegeneration Research Group. His academic journey spans multiple international institutions, including previous research positions at the University of California Los Angeles (UCLA), Mahidol University in Thailand, and Hallym University in South Korea.

Dr. Dutta's research focuses on extracellular vesicle biology, particularly analyzing brain-derived blood exosomes in neurodegenerative diseases such as Parkinson's disease and Multiple System Atrophy. His work aims to isolate and characterize exosomes released by specific brain cells into the bloodstream and identify signature biomolecules that could serve as diagnostic tools. His current research specifically targets biomarker discovery for stratifying Parkinson's disease using EVs from iPSC-based models and patient samples.

His publication record shows a strong focus on exosome-based biomarker development for neurodegenerative diseases, with recent work emphasizing α-synuclein pathology, novel detection methodologies like electrochemiluminescence ELISA, and the challenges of translating EV research into clinical diagnostics. His research bridges molecular neuroscience with practical diagnostic applications.

Dr. Dutta's scientific contributions center on developing blood-based diagnostic approaches for neurodegenerative conditions, with particular emphasis on differentiating between similar disorders like Parkinson's disease and Multiple System Atrophy through exosome analysis. His work represents a promising avenue for non-invasive diagnostics in neurology.

His research methodology combines advanced techniques including ultrasensitive electro-chemiluminescent ELISA, miRNA assays, mass spectrometry, lipidomics, and SIMOA technology to characterize exosomal cargo. This multidisciplinary approach positions his work at the intersection of molecular neuroscience, diagnostic technology development, and clinical neurology.