Steven Weinman

Steven Weinman is a Professor in the Department of Internal Medicine and Gastroenterology, Hepatology & Motility Division at the University of Kansas Medical Center School of Medicine. As Director of the Liver Center and Vice Chair for Research, he leads clinical studies and tissue banking initiatives.

• BA in Biochemistry, Harvard University
• MD-PhD (Medicine & Cell Biology), Washington University
• Internal Medicine Residency, Yale University

His research explores macrophage roles in alcohol-associated liver disease, focusing on Kupffer cell heterogeneity and C/EBPβ-HDL interactions. Collaborative work with Salman Khetani (UI Chicago) utilizes micropatterned co-cultures for liver cell communication studies.

• NIH NIAAA Grant: Kupffer Cell Adaptation in ALD
• KC-MORE Grant (NIH): Metabolism-Alcohol Interactions

Notable contributions include demonstrating HCV mitochondrial interactions and identifying lysine demethylases as gender-specific drivers of liver fibrosis. Awards: KU Research Investigator Award, Excellence in Mentoring Award (2019).

Labs on the 4th floor of Hemenway Life Science Center house a multidisciplinary team studying liver disease mechanisms:

• Sheetalnath Rooge (Postdoc, Kupffer Cell Hepatoprotection)
• Isabel Pulido Ruiz (Research Associate, Macrophage Targeting)
• Heer Mehta (Medical Student, CD163+ Kupffer Cells)
• Kyo Sasaki (Former Postdoc, now Assistant Professor in Japan)
• Zhuan Li (Former Postdoc, XiaoXiang Professor in China)