معرفی
Professor Steve Wedge is a prominent academic at Newcastle University specializing in cancer research with a focus on molecular targeting, drug development, and radiation therapy combinations. His work spans preclinical modeling, clinical trials, and mechanistic studies of kinases like MDM2, ERK5, and Aurora kinases.
- Key research areas: Oncology, Pharmacology, Molecular Targeted Therapy, and Angiogenesis Inhibition
- Active in clinical trial design (e.g., AZD3965 for advanced cancer) and kinase inhibitor discovery (ERK5, MDM2)
- Collaborates extensively on combination therapies with radiotherapy and chemotherapy
His recent publications highlight advancements in MDM2-p53 interaction inhibition, metabolic targeting of tumors, and DNA-encoded library screening for drug discovery. Awards and mentoring activities remain undocumented in this dataset.
۰مقاله ثبتشده