Stephan Kröger

Prof. Dr. Stephan Kröger serves as Professor and Research Group Leader of "Physiological Genomics" at the Institute for Physiology, Ludwig-Maximilians-University Munich, operating within the BioMedical Center (BMC) in Planegg-Martinsried. As a Regular member of MCN and GSN full member, he maintains active laboratory operations at Großhaderner Str. 9 with direct contact channels including email stephan.kroeger@lrz.uni-muenchen.de and phone +49 (0)89 / 2180-71899.

His research program centers on the cellular and molecular architecture of neural development, with particular emphasis on extracellular matrix dynamics during nervous system formation. Critical investigation areas include pathological nervous system manifestations in muscular dystrophy, developmental mechanisms of muscle spindles, and molecular foundations of synapse assembly at both neuromuscular junctions and central nervous system synapses. This work bridges structural neurobiology with functional pathophysiology, generating significant insights into neuromuscular communication systems through rigorous molecular and cellular experimentation.

Publication analysis (2009-2015) reveals consistent focus on agrin-mediated signaling pathways across neuromuscular development, with particular emphasis on muscle spindle specialization and autoimmune disruption mechanisms. His work demonstrates sophisticated integration of developmental biology, molecular neuroscience, and clinical neurology, establishing critical links between extracellular matrix components and synaptic organization defects in conditions like myasthenia gravis and muscular dystrophy.

Leading the "Physiological Genomics" research group, Kröger directs comprehensive investigations into genetic and molecular determinants of neural-muscular interface development. His laboratory employs advanced cellular imaging, molecular genetics, and electrophysiological techniques to dissect synaptogenesis mechanisms, with particular attention to agrin-dependent signaling cascades and their pathological implications in neuromuscular disorders.