Stefan Both

Prof. Stefan Both is a Professor in the Faculty of Medical Sciences at the University of Groningen, affiliated with the University Medical Center Groningen (UMCG). His primary role is within the Department of Personalized Cancer Treatment, focusing on advancing proton therapy and radiation oncology. He leads research in areas such as proton beam range verification, biological dose modeling, and AI-driven treatment planning. His work emphasizes reducing treatment toxicity and improving outcomes for head and neck, brain, and nasopharyngeal cancers.

Research Interests:

• Proton therapy optimization and clinical implementation
• Biological effects of radiation and dose modeling (LET/RBE)
• Advanced imaging techniques (PET/CT) for treatment verification
• Deep learning applications in radiation oncology
• Clinical trials on proton arc therapy and FLASH irradiation

Awards:

• BEST IN PHYSICS (Therapy) Award for real-time proton range verification via 12N imaging
• Editor’s Choice Article in Physics in Medicine and Biology for Monte Carlo simulation frameworks

Grants & Collaborations:

Collaborates with institutions like IBA (Ion Beam Applications) and the PARTREC research group. Active in multi-institutional studies on proton therapy protocols and clinical trials for proton arc therapy. Leads research on FLASH irradiation for breast and prostate cancers.

Labs & Teams:

Leads the Personalized Cancer Treatment lab at UMCG, focusing on translational research in radiation oncology. Engages in interdisciplinary teams for AI integration and proton therapy innovation.