Stanislav Rubakhin

Stanislav Rubakhin is a Research Professor in Chemistry at the University of Illinois Urbana-Champaign, affiliated with the Beckman Institute. His work focuses on advancing mass spectrometry techniques for biological applications, particularly in neurochemistry and proteomics. He develops cutting-edge methods like MALDI imaging, single-cell analysis, and microfluidics-based systems to study neuropeptides, proteoforms, and lipid distributions in neural tissues.

Research Interests: Rubakhin specializes in mass spectrometry imaging (MALDI-TOF, TIMS), single-cell proteoform profiling, and the study of posttranslational modifications (e.g., isoaspartate formation) in neuroactive peptides. His work bridges analytical chemistry with neuroscience, enabling spatial and molecular resolution of biological processes in brains and peripheral tissues.

Recent work highlights neurochemical comparisons of motor nerve organoids, lipid mapping in Alzheimer’s disease models, and the use of 1-octanol microfluidics for enhanced sample handling. Collaborations span neurobiology, biochemistry, and biomedical engineering, with datasets published through the University of Illinois.

Lab Affiliations: Beckman Institute for Advanced Science and Technology, where he contributes to interdisciplinary projects in biotechnology and analytical instrumentation.