Jonathan V Sweedler

Jonathan V Sweedler is the James R. Eiszner Family Endowed Chair in Chemistry and Professor at the University of Illinois, holding dual appointments in Neuroscience and Molecular & Integrative Physiology. As Director of the School of Chemical Sciences and affiliated with the Beckmann Institute, he leads interdisciplinary research in analytical chemistry, neurochemistry, and single-cell analysis.

His primary research focuses on developing advanced mass spectrometry technologies for probing neurochemical systems, including neuropeptide mapping, proteoform analysis, and spatial metabolomics. Key innovations include MALDI imaging techniques for single-cell resolution and high-throughput workflows for large-scale biochemical profiling.

Notable achievements include:

• World's Top 100 Analytical Scientist (2021)
• $5.6M NIH grant for addiction neurochemistry research
• Over 200 peer-reviewed publications since 2020

Current projects span neurodegenerative disease biomarkers, microbial biofilm metabolomics, and automated genome engineering for lipid production. His lab collaborates globally across chemistry, biology, and engineering disciplines.

Labs/Teams: Sweedler Research Group, Beckmann Institute Neuroengineering Core, University of Illinois Mass Spectrometry Center.