Srinath Chinnakotla

Srinath Chinnakotla is a Professor in both the Department of Surgery and the Department of Pediatrics at the University of Minnesota School of Medicine. His clinical and academic work is centered on complex pancreatic and liver transplant procedures, particularly in pediatric and adult patients with chronic pancreatitis. He is a key contributor to the University of Minnesota’s Clinical Center for the Study of Pancreatic Disease and actively participates in multicenter research collaborations such as the POST Consortium.

His research interests include:

• Total Pancreatectomy with Islet Autotransplantation (TPIAT)
• Islet cell isolation and transplantation
• Chronic pancreatitis management
• Liver transplantation in pediatric patients
• Immunosuppressive regimens including tacrolimus and everolimus
• Long-term metabolic outcomes post-pancreatectomy

Dr. Chinnakotla’s recent publications highlight advancements in continuous glucose monitoring, pain management, and long-term graft function following TPIAT. His work emphasizes improving quality of life and insulin independence in patients undergoing radical pancreatic surgery.

His research has been funded by prestigious agencies including the National Institutes of Health (NIH) and industry partners such as Novartis and Genentech. Notable projects include:

• University of Minnesota Clinical Center for the Study of Pancreatic Disease (NIH-funded, 2020–2025)
• Advancing Treatment for Pancreatitis: A Prospective Observational Study (NIH, 2016–2024)
• Randomized controlled trial of tacrolimus and everolimus in liver transplantation (Novartis, 2014–2019)
• Reduced exposure study in pediatric liver transplant (Novartis, 2013–2016)
• Multicenter cohort study on renal transplant recipients (Genentech, 2011–2016)

He has delivered invited presentations on multidisciplinary approaches to pediatric liver transplantation and collaborates extensively with experts in endocrinology, surgery, and immunology. Dr. Chinnakotla plays a central role in advancing clinical protocols and evidence-based practices in transplant surgery.