معرفی
Sravan Perla is an Associate Research Scientist in the Department of Pharmacology at Yale School of Medicine, where he conducts research under the mentorship of Dr. Anton Bennett. His work focuses on elucidating the molecular mechanisms of Protein Tyrosine Phosphatases (PTPs) in congenital heart diseases and metabolic regulation.
- Education: Ph.D. in Molecular Medicine and Pathology from New York Medical College and the University of Toledo; M.Sc. in Medical Biochemistry from JIPMER, India; B.Sc. in Biochemistry from Silver Jubilee Govt. Degree College.
His primary research interests include cardiovascular signaling pathways, particularly the PZR/Shp2/Irx3/Irx5/BMP10 axis in Noonan Syndrome and related disorders. He investigates epigenetic regulation of genes like angiotensinogen and explores therapeutic interventions such as low-dose dasatinib and recombinant BMP10 for hypertrophic cardiomyopathy. His work bridges molecular pharmacology and translational medicine.
The recent publications highlight a strong trend in signal transduction, cardiovascular pathophysiology, and therapeutic repurposing, with a focus on tyrosine phosphatases and TGF-β pathways. His research also extends into neurological applications, as seen in his co-authored work on post-stroke seizures.
- Best Poster Presentation, Yale Center for Molecular and Systems Metabolism (YMSM), 2024
- Armed Forces Medical College Quiz Award, Association of Clinical Biochemists of India, 2010
Sravan Perla actively contributes to peer review for journals including Frontiers, Healthcare-MDPI, and International Journal of Environmental Research and Public Health. He is a key member of the Bennett Laboratory, where he advances research on PTP signaling and its implications for human disease. His work is supported by institutional affiliations at Yale and collaborative networks across neuroscience and cardiology.
