معرفی
Sophie Payne is a Postdoctoral Research Scientist in the Department of Physiology, Anatomy and Genetics at the University of Oxford, affiliated with the De Val Group. Her work centers on coronary vessel formation and revascularization in damaged hearts, investigating why natural vessel regrowth fails after myocardial infarction and identifying therapeutic pathways to improve ischemic tissue survival.
Her research spans cardiovascular biology, vascular development, regenerative medicine, molecular biology, endothelial biology, and epigenetics. She examines regulatory mechanisms controlling coronary vascular growth in healthy and diseased hearts, with recent work identifying three independent pathways governing vessel development and exploring their reactivation for therapeutic revascularization.
Analysis of her publications reveals a consistent focus on molecular regulation of vascular development, exemplified by her 2021 study on ETS factors and endothelial enhancer activity. This work integrates developmental biology and epigenetics to understand cell-type-specific gene regulation in vascular formation.
No scientific awards are documented in the provided materials.
She is currently funded by a British Heart Foundation 3-year project grant supporting her research on coronary revascularization pathways. No student advisement information is available.
Payne operates within the De Val Group laboratory, which specializes in cardiovascular development and disease mechanisms, utilizing molecular and genetic approaches to study heart formation and repair.
