Sobha Sivaprasad

Sobha Sivaprasad serves as an Honorary Professor at University College London's Institute of Ophthalmology and concurrently holds a Consultant position in Ophthalmology at Moorfields Eye Hospital NHS Foundation Trust within the Medical Retina and Research department. Her dual academic-clinical appointment spans since October 2015 at UCL and April 2011 at Moorfields, reflecting deep integration between research and clinical practice in ophthalmology.

Her research interests center on diabetic retinopathy, age-related macular degeneration, and retinal imaging technologies. Current work focuses on diabetic macular ischemia, visual outcomes in AMD, novel therapeutic targets like the Sema3A/Nrp1 pathway, and comparative effectiveness of anti-VEGF therapies versus traditional laser treatments. Her publication record demonstrates strong emphasis on multicenter clinical trials, real-world evidence studies, and methodological innovations in retinal disease assessment.

Analysis of her recent publications reveals significant contributions to understanding visual function determinants in early AMD, development of new diabetic retinopathy screening protocols, and evaluation of emerging treatments for conditions like central serous chorioretinopathy. Her work frequently addresses healthcare delivery innovations, including community-based asynchronous review models that reduce appointment delays across hospital networks.

Professor Sivaprasad actively contributes to major collaborative studies including PEONY, INSPIRED, INTERCEPT-AMD, and HORNBILL initiatives. Her research integrates genetic risk assessment with clinical phenotyping, particularly through polygenic risk score analyses in aging-related eye disease.