معرفی
Slav Bagriantsev is a Professor in the Department of Cellular & Molecular Physiology at Yale School of Medicine. His research focuses on mechanotransduction, sensory receptor biology, and physiological adaptations in hibernation. Bagriantsev holds a PhD from the University of Illinois at Chicago and completed postdoctoral training at the University of California, San Francisco (2012). He leads the Slav Lab, investigating touch sensation mechanisms and hibernation physiology in animals like ground squirrels.
Research Interests: His work explores how mechanosensitive ion channels mediate touch detection in specialized sensory organs (e.g., Pacinian corpuscles), and how hibernating mammals survive extreme conditions without water or food. Key projects include studying neural adaptations enabling months-long torpor states and identifying molecular mechanisms underlying cold tolerance.
Publications Trends: Recent work emphasizes structural biology of touch receptors and neuroendocrine regulation during hibernation. Notable findings include the discovery of how ground squirrels suppress thirst mechanisms and the role of hypothalamic hormones in physiological anorexia during torpor.
Awards:
- National Science Foundation CAREER Award (2015)
- American Heart Association Scientist Development Grant (2014)
- Genentech Foundation Postdoctoral Fellowship (2009)
Advising & Lab: The Slav Lab collaborates with researchers like Elena Gracheva and Yury Nikolaev, focusing on interdisciplinary projects combining electrophysiology, structural biology, and animal behavior. Current efforts aim to translate hibernation biology insights into human medical applications like organ preservation and metabolic therapy.
