معرفی
Simonetta Gribaldo is a Principal Investigator at the Institut Pasteur in Paris, France, within the Department of Microbiology. She leads a research group focused on Evolutionary Biology of the Microbial Cell, particularly investigating the evolutionary history and biogenesis of anaerobic bacteria and archaea.
- Phylogenomic analysis of microbial diversity
- Archaeal cell biology and envelope evolution
- Human microbiome and pathogen interactions
Research Interests: Her team specializes in cutting-edge phylogenomic approaches to resolve ancient divergences in Bacteria and Archaea, reconstruct evolutionary relationships between life domains, and discover novel microbial clades. Current experimental research includes studying methanogens and diderm Firmicutes as human microbiota model organisms.
Key Projects: Leading initiatives like ENVOL (envelope evolution), VIROMET (archaeal virome), and Fir-OM (outer membrane transition). Collaborations include work on Methanoperedens host-Borg element interactions and Negativicutes LPS-outer membrane studies.
Technical Expertise: Utilizes nanopore sequencing, phylogenetic inference, and experimental validation to complement computational analyses. Research addresses major evolutionary transitions and challenges established paradigms in microbial evolution.
